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Dr. Samira Mohammad Mirzapour

Faculty Of Dentistry Education and Treatment Center-Assistant Professor of Periodontics

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Research Interests

Keep in touch

بخش پریو دانشکده دندانپزشکی تبریزmirzapour.s@gmail.com--

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Books (Authoring, Compilation, Translation)

Role of Regenerative Medicine in the Treatment of Diseases

Book Type:Authoring-Institution:Kindle-Publication Date:June 1, 2023
Description:Regenerative medicine is a rapidly evolving field that aims to restore, replace, or regenerate damaged tissues and organs using advanced biomedical techniques. It holds the potential to revolutionize healthcare by providing innovative solutions for a wide range of medical conditions that were previously considered incurable or difficult to treat. The fundamental principle of regenerative medicine is harnessing the body's innate healing mechanisms to stimulate tissue repair and regeneration. The field of regenerative medicine encompasses various approaches, each offering unique opportunities to address different aspects of tissue regeneration and repair. Stem cell therapy is one such approach. Stem cells are undifferentiated cells with the ability to differentiate into specialized cell types. They hold immense potential for regenerative medicine as they can be directed to become specific cell types required for tissue repair. Stem cell therapies have shown promising results in treating conditions such as spinal cord injuries, heart disease, and certain types of cancer. Tissue engineering is another crucial aspect of regenerative medicine. It involves combining cells, scaffolds, and growth factors to create functional tissue constructs. These constructs can be used to replace or repair damaged tissues and organs. Tissue engineering approaches have been successfully applied in the regeneration of skin, cartilage, bone, and blood vessels. Gene therapy is a promising avenue within regenerative medicine. It aims to correct or replace defective genes that cause disease. By introducing functional genes into targeted cells, gene therapy can potentially treat genetic disorders and promote tissue regeneration. This approach has shown promise in treating diseases such as cystic fibrosis, muscular dystrophy, and certain types of cancer. Biomaterials play a crucial role in regenerative medicine by providing a supportive environment for tissue regeneration. These materials can be used as scaffolds to guide cell growth, deliver therapeutic molecules, and promote tissue integration. Biomaterials have been utilized in applications such as bone regeneration, wound healing, and organ transplantation. The role of regenerative medicine goes beyond treating diseases and injuries. It also offers potential solutions to mitigate the shortage of organ donors, reduce the need for immunosuppressive drugs, and improve the quality of life for patients with chronic conditions. By stimulating the body's natural healing processes, regenerative medicine aims to restore normal tissue function rather than merely managing symptoms. Despite significant progress, challenges remain in the field of regenerative medicine. Ensuring the safety and efficacy of new therapies, optimizing manufacturing processes, and addressing regulatory and ethical considerations are ongoing concerns. However, with continued research, technological advancements, and collaborative efforts among scientists, clinicians, and regulatory authorities, regenerative medicine holds the promise of transforming the landscape of healthcare and providing innovative treatments for currently untreatable conditions. In conclusion, regenerative medicine has emerged as a multidisciplinary field with the potential to revolutionize healthcare. Through approaches such as stem cell therapy, tissue engineering, gene therapy, and biomaterials, regenerative medicine aims to restore tissue and organ function, offering new hope for patients with previously incurable conditions. Continued research and advancements in this field have the potential to significantly impact the future of medicine.

Publications and Conferences

Title of Article / Authors / Journal
Publication Year

Stem cell therapy for regenerating periodontal bony defects: A narrative review

Samira Mohammad Mirzapour, Fatemeh Jalali

Journal of advanced periodontology and implant dentistry

2025-03-03T18:56:32.179Z

Effect of the Bone Graft on the Surface Microhardness of Endodontic Biomaterials

Samira Mohammad Mirzapour, Shahriar Shahi, Saeed Rahimi, Hamid Reza Yavari, Negin Ghasemi, Yashar Rezaei

Iranian Endodontic Journal

2018-04-09T17:52:53.309Z

Comprehensive periodontal treatment in generalized stage iv, grade c periodontitis: a clinical case report

Samira Mohammad Mirzapour, Sahar Chokami Rafiei, Jowel Makdisi

Brazilian Dental Science

2020-12-22T18:48:35.415Z

The Effect of Non-Surgical Periodontal Therapy on Pentraxin-3 Concentration in Gingival Crevicular Fluid of Chronic Periodontitis Patients: A Clinical Trial

Samira Mohammad Mirzapour, Asieh Mozaffari, Mahtab Samieifar, Bahare Abd Nikfarjam, Monirsadat Mirzadeh, Shadi Assareh

Journal of dentistry

2022-09-23T18:46:03.567Z

Cytotoxicity of PLGA-zinc oxide nanocomposite on human gingival fibroblasts

Samira Mohammad Mirzapour, Asieh Mozaffari, Motahare Sharifi Rad, Mehdi Ranjbaran

Journal of advanced periodontology and implant dentistry

2023-06-03T18:43:03.630Z

Stem cell therapy for regenerating periodontal bony defects: A narrative review

Samira Mohammad Mirzapour, Fatemeh Jalali

Journal of advanced periodontology and implant dentistry

2025-03-03T18:40:30.615Z

Effect of autogenous tooth vs. autogenous bone grafts on periodontal phenotype around immediate implants: A randomized clinical trial

Samira Mohammad Mirzapour, Adileh Shirmohammadi, Elnaz Ziaei-Rad, Leila Roshangar, Fatemeh Aghaziarati

Journal of advanced periodontology and implant dentistry

2025-12-02T18:37:21.038Z

The Effect of Licorice Extract on Clinically Isolated Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis

Samira Mohammad Mirzapour, Mohammad Yousef Memar, Sepideh Bohlouli, Islam Nasiri, Hadi Eslami, Solmaz Maleki Dizaj, Simin Sharifi

Infectious Disorders Drug Targets

2026-03-13T18:34:01.307Z

Development and evaluation of a PLGA/TiO2 nanocomposite for periodontal applications: Synthesis, characterization, and cytocompatibility with human gingival fibroblasts—An in vitro study

Samira Mohammad Mirzapour, Atabak Kashefimehr, Motahare Sharifyrad, Samira Beiraghisalek

Journal of advanced periodontology and implant dentistry

2026-02-18T18:29:27.918Z

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